Autologous regenerative therapy · Mill Street

Seffiline®

Your own tissue, used to support regeneration.

This technique uses the patient's own micro & nano purified fat to restore tissue quality, improve dermal structure and support long term skin integrity. It is a completely natural regenerative form of aesthetic medicine, using only your own natural stem cells, growth factors and exosomes.

Book a specialist consultation Explore the process

Treatment

Autologous fat transfer

Procedure

About 1 hour

Led by

Dr Lorenzo, Dr Daniella & Dr Vishal

Seffiline® at SE1

Dr Lorenzo Garagnani MBE preparing a Seffiline procedure

A one-stop regenerative treatment using your own tissue.

What is Seffiline®?

Make use of your own regenerative cells.

Seffiline® is an all-in-one, disposable medical device for Autologous Regenerative Therapy.

The procedure involves extracting your own fat tissue (adipose tissue) and using the naturally occurring stem cells, exosomes and growth factors within it for various regenerative treatments.

The core technology uses a patented guiding cannula system, known as the Superficial Enhanced Fluid Fat Injection (SEFFI) technique, which simplifies the process and ensures tissue is harvested from the correct depth to maximise the viability of the regenerative cells.

The Seffiline® system

The primary advantage of the Seffiline® system is that it makes sophisticated regenerative procedures safer, more standardised, and accessible to patients.

01 · Seffiline® kit

SEFFILLER®

Used in aesthetic medicine for facial anti-ageing treatments.

02 · Seffiline® kit

SEFFIHAIR®

Used for the treatment of hair loss and alopecia, with Dr Vishal Aggarwal.

Explore hair restoration

Seffilline® procedures are minimally invasive, walk-in, walk-out treatments performed under local anesthesia in our CQC registered Bermondset Street clinic, typically lasting an hour. It is an autologous fat transfer method using your own tissue to rejuvenate the tissue.

Book a specialist consultation with Dr Lorenzo, Dr Daniella or Dr Vishal

Seffihair® before & after

Seffihair® hairline before and after 1 session

Book a Seffihair® consultation

The three-stage process

Harvest, prepare, then re-implant.

Harvesting the adipose tissue

Donor Site Selection

A small amount of superficial fat tissue is typically taken from areas where it is more compact, such as the outer thigh or abdomen.

Anesthesia

A local anesthetic is administered to the donor area to ensure the procedure is comfortable and pain-free.

Collection

A specialised, small-diameter (0.8 mm side port holes) micro-cannula within a patented guide is inserted into the superficial adipose layer. The guide standardises the depth of collection (around 15 mm below the skin) to access tissue rich in Adipose-Derived Stem Cells (ADSCs). A gentle negative pressure (using a specific syringe with a plunger lock) is used to extract the fat in small, micro-fragmented clusters, which preserves cell viability and ensures the tissue is already fluid.

Preparation and processing

Minimal Manipulation

The collected tissue is transferred to a reservoir syringe and mixed with a saline solution.

Decantation

The syringe is placed vertically for approximately five minutes to allow the contents to stratify by gravity, separating the fat tissue from the washing liquid and any free oil.

Washing

The washing liquid (containing blood and lidocaine) is discharged, leaving the purified, stem cell-enriched micro-fat ready for injection. No complex or traumatic processing like centrifugation or enzymatic digestion is required, which helps maintain the regenerative properties of the tissue.

Re-implantation (grafting)

Recipient Area Preparation

The targeted facial areas (e.g., cheeks, temples, jawline, chin, periocular area or any thinning hair area) are disinfected, and a local anesthetic may be used.

Injection

The prepared micro-fat is transferred into smaller, fine-gauge cannulas. Your doctor strategically “sows” the fat in small aliquots into the superficial subcutaneous layer using a fanning, retrograde technique. This careful placement avoids creating lumps and ensures optimal integration and re-vascularisation of the graft by the surrounding host tissue.

Post-Procedure

The treated area may be gently massaged for even distribution.

Seffiline® autologous regenerative therapy

What happens next

Regeneration develops over time.

The regenerative action of the stem cells improves skin quality (tone, elasticity, and radiance) over the following weeks and months, with peak results typically visible after 2 to 4 months.

Uses your own tissue
Micro & nano purified fat
Facial rejuvenation and hair restoration applications

Book a consultation Explore all treatments

Seffihair®

Your own cells, working for your scalp.

Rather than masking hair loss, Seffihair® addresses the underlying biological environment of the scalp, helping to reactivate and support natural hair growth. With Dr Vishal Aggarwal.

How it works

Harvesting

A gentle local anaesthetic procedure to harvest a small amount of your own fat, usually from the outer thigh.

Processing

The tissue is processed using a specialised filtration system, purifying the regenerative cells and growth factors it contains.

Re-injecting

The purified regenerative component is re-injected into the scalp, helping to reactivate and support natural hair growth.

Designed to

Improve hair density
Stimulate dormant hair follicles
Strengthen thinning hair
Improve scalp health

Particularly effective for

Early-stage male and female pattern hair loss
Postpartum hair thinning
Hair thinning due to stress or hormonal changes

Because the treatment uses your own cells, there is no synthetic material, minimal risk of allergic reaction and a highly natural looking outcome.

Before & after

Book a Seffihair® consultation

Seffiline® · SE1 Medical Aesthetics London

Start with a specialist consultation.

Book with Dr Lorenzo, Dr Daniella or Dr Vishal