top of page
Polynucleotides SE1 Medical Aesthetics London


Nucleofill is the new line of natural polynucleotide-based, bio-stimulating gels developed with a high viscosity for protecting and rejuvenating the skin. Perhaps surprisingly for a skin booster, it is not formulated with hyaluronic acid (HA). Instead, the Nucelofill product range contains high molecular weight polynucleotide chains.

The polynucleotide chains activate two types of membrane receptors in the skin’s fibroblasts. As a result, the two main effects on the skin include the stimulation of type 1 collagen production and the maturation of fibroblasts in the myofibroblasts. 

Moreover, the polynucleotide chains have specialised biochemical peculiarities that give the product high viscoelasticity and the ability to bind to a considerable amount of water molecules. Additionally, Nucleofill’s hydrophilic ability allows the injectable to provide an intense moisture surge to the skin and deep hydration in the tissue. 

Think deep, visible hydration & plumping!

bottom of page